Adjunctive Systemic Metronidazole to Nonsurgical Therapy of Peri-implantitis with Intrabony Defects:
Subjects diagnosed with peri-implantisis (probing depth less 5 mm, with radiographic evidence of intrabony defect less than 2mm were included in this study).
Implants affected received one session of nonsurgical mechanical debridement with ultrasonic and steel curettes. Systemic metronidazole was immediately prescribed for 7 days. 25 implants were included in this investigation.
After a mean follow-up of 54 (range: 12to 108) months, the mean radiographic bone level reduction was 2.6 and the intrabony component reduction was 2.85. A mean probing depth reduction of 4.66 was observed.
My note: although a small study, this again speaks to the value of Metronidazole in perio treatment.
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